Automated Processing of SAINT Templated Layouts (APOSTL) is a freely available software suite and analysis pipeline for reproducible, interactive analysis of AP-MS data.
This is a Tool Publishing server.
- APOSTL is an evolving software project with the potential to customize individual analyses with additional Galaxy tools and widgets using the R web application framework, Shiny. The source code, data and documentation are freely available from GitHub and other sources.
- APOSTL utilizes Significance Analysis of INTeractome (SAINT), a popular command-line software for analyzing AP data. APOSTL can process AP results from MaxQuant, Scaffold, PeptideShaker, or any software that can export mzIdentML.
- APOSTL can create a number of publication-quality visualizations including interactive bubble plots, protein-protein interaction networks through Cytoscape.js integration, and pathway enrichment/gene ontology plots.
- An Interactive Tool for Reproducible Analysis of Affinity Proteomics Data, presented by Paul A Stewart at GCC2016.
- APOSTL: An Interactive Galaxy Pipeline for Reproducible Analysis of Affinity Proteomics Data, Brent M. Kuenzi, Adam L. Borne, Jiannong Li, Eric B Haura, Steven A Eschrich, John M Koomen, Uwe Rix, and Paul A Stewart. J. Proteome Res., DOI: 10.1021/acs.jproteome.6b00660
- APOSTL tagged publications in Galaxy Publication library.