It is a very busy time in the Galaxy. 2021 is young, but we have already had two large training events, including the largest Galaxy event ever - the GTN Smörgåsbord (with an amazing 1100+ people registered). We are ramping up for GCC2021, which will be online, global, and affordable, and will be more accessible (and likely much larger) than an in-person Galaxy Community Conference.
Galaxy is also shifting with the times, and to reflect how our community has grown. This newsletter includes a new Featured News section highlighting 1) the recent explosion of videos related to Galaxy, 2) a draft global governance model for Galaxy, and 3) the new Galaxy Career Center.
That's followed by another new section highlighting community news. Arguably, everything here is community news, but items listed here particularly emphasize the community aspects of Galaxy.
The newsletter still includes sections on
- upcoming events,
- news about public Galaxy platforms,
- recent blog posts,
- training and doc updates,
- recent open-access Galaxy-related publications, and
- new releases.
It's a lot to take in, but it all highlights the breadth and depth of the Galaxy Community.
Dave Clements and Beatriz Serrano-Solano, Editors
When Galaxy started, screencasts were a big part of our documentation and training. Fifteen years later videos have returned to Galaxy with a vengeance. This is partly due to the pandemic, and partly due to a long term global shift towards recording events, and towards creating short demonstration and introduction videos.
A number of notable videos and video collections have recently been published:
- This collection of 43 videos was created for the recently completed Galaxy Smörgåsbord training event. They cover a huge sample of the Galaxy Training Network materials.
- This collection of 27 videos was created for the also recently completed 2021 Galaxy Admin Training event. Everything you ever wanted to know about administering your own Galaxy instance (well, almost).
- Nine videos (and growing), each under 3 minutes, providing brief introductions to commonly used features of Galaxy.
- Covers a wide range of galaxy features. Videos range from 24 seconds (History: Sharing via link) to 12 and half minutes (Galaxy and NGS)
- Recordings of Galaxy Webinars and Workshops are spread across the web. This playlist attempts to list recent webinars that we know about that are on YouTube. This list is brand new and is rapidly expanding.
- Videos that introduce the Galaxy community.
In December, Galaxy introduced Working Groups, community-driven small groups that manage different aspects of the Galaxy Ecosystem. Working groups set quarterly milestones for their areas, distribute work, and meet to discuss progress and roadblocks. Working Groups were launched in late 2020. If you want to contribute to Galaxy in a big way, please join one or more Working Groups.
This month we are introducing the first draft of a Galaxy Governance Model that includes Working Groups as a key component. The model also includes the new Galaxy Exec, the Global Galaxy Steering Committee, and incorporates the longstanding Committers Groups.
Our hope is that this framework will enable us to become a truly global community.
The recently completed GTN Smörgåsbord course was the largest Galaxy event ever, and it was absolutely incredible.
- 1,189 people from 76 countries
- 583 people on slack
- 60+ instructors
- 25 hours of video, all with closed captioning, which were used by 45% of participants
- 24 hour coverage for a week
We strongly encourage you to read the full event report. It's amazing.
The recently opened Galaxy Career Center lists every Galaxy Related opening we know about. Each posting (and there are 10 that are currently open) includes a short description, a link to the full posting, and deadlines, when known. There are openings at
- GalaxyWorks, University of Minnesota, Cleveland Clinic, and Johns Hopkins University (3 positions)
- Incliva (24 March), INSERM (1 April), and Hannover Medical School
The first round of EOSC-Life demonstrators has driven eight successful use cases, three of them using Galaxy:
- European Open Science Cloud resources for Chemical Biology and Structure-Based Drug Discovery workflows
- Marine Eukaryote Genomics Portal – access to tools and data-flows for marine genome annotation
- Image Repository and Scaleable Mining
Has launched! If you are part of the Czech computational analysis community then please consider getting involved by:
We would like to reintroduce the newly updated Galaxy Gateway powered by F1000Research. This Gateway offers an accessible home for all research outputs. You can rapidly publish your Galaxy-related presentations for free. The Gateway has been the recommended venue for publishing GCC slides and posters since GCC2016. It's a great way to improve the visibility and accessibility of your research, and you will receive a DOI too.
F1000Research is an open access publishing platform supporting data deposition and sharing. The Galaxy Gateway enables you to accelerate the impact of your work. Discover this month's highlighted paper (and see Platforms and Publications below too).
And we need your help!
- Please add suggestions for projects here (or send them to Dave Clements).
- Please apply to work on Galaxy projects between March 29 and April 12.
The January Papercuts CoFest offered prizes for 10 randomly selected contributors. The winners are:
- Catherine Bromhead, University of Melbourne
- Helena Rasche, ErasmusMC
- Anthony Bretaudeau, INRAE
- Oleg Zharkov, University of Freiburg
- Saskia Hiltemann, ErasmusMC
- Estelle Ancelet, INRAE
- And 4 anonymous
The calendars actually start in March 2021. You can order one too.
The Galaxy community has recorded different ways of joining us, with suggestions for newcomers.
Despite COVID-19, there is still a lot going on, and most of it is online. See the full list of events. Some highlights:
3, 10, 17, 24 March
Galaxy-ELIXIR webinars series: Advanced Features
With this series of four webinars chaired by Hans-Rudolf Hotz, the global Galaxy community will present advanced features that may have remain unknown due to the rapid developments in every Galaxy release. The series will touch upon workflows, data processing and management, interoperability and interactive tools, among others.
Advanced Galaxy workflow features, 3 March, watch the video
Processing thousands of datasets simultaneously, 10 March watch the video
Galaxy bridge to Jupyter notebooks and RStudio, 17 March
Speed up your data analysis with Galaxy: Features no one knows about, 24 March
GCC2021 will start on 28 June with a week of online training. Training will largely use the GTN Smörgåsbord model: Lectures will be prerecorded, with live help available on chat for the duration of the week. This model allows participants to learn at their own pace, avoids scheduling conflicts that are inherent with our usual multi-track training, and enables those with low bandwidth internet connections to fully participate.
We also expect to open registration and abstract submission shortly. Registration discounts will be available to researchers from low and lower-middle income countries. For everyone else, registration will be downright cheap too. We will reuse the BCC2020 model for talks, posters, and demos: Posters and demos will be live (sometimes in both hemispheres), and talks will be prerecorded.
And GCC2021 is looking for sponsors too!
Please watch Galaxy channels for the registration and abstract submission announcements.
23 March, 7 April, or 13 April
ELIXIR Norway is pleased to announce the first online course on using the Norwegian e-infrastructure for Life Science (NeLS) and the nationally supported usegalaxy.no. There are 3 identical events. Please register for only one of them.
This workshop is open to everybody interested in Galaxy and has two independent parts (Intro, and Proteomics-specific). Please feel free to join any or both. But you do need to register as space is limited.
18 March, Online, Global
Please join us for the 6th Papercuts CoFest day on March 18 to help the Galaxy Ecosystem become a better place, and to help new contributors come on board.
There next roundtable meetup will be:
March 18: Bringing GPU support to Galaxy, Jashwant Raj and Gulsum Gudukbay will discuss the integration of GPU Resources in Galaxy for accelerating tool executions.
Deadline: 1 April
Galaxy has always had a strong presence at Biohackathon Europe. We hope this tradition will continue in November 2021. Get your proposals in now.
Feel charged up while discussing mass spec and proteomics? Please join us on this call to learn more about the Galaxy Mass Spec Community. The next meeting is on April 1st (not a fool’s joke) at 1 PM UTC / 12 noon GMT. See the agenda for details and joining instructions.
Galaxy Platforms News
The Galaxy Platform Directory lists resources for easily running your analysis on Galaxy, including publicly available servers, cloud services, and containers and VMs that run Galaxy. Here's the recent platform news we know about:
ASaiM integrates and hierarchically organizes metagenomic and metatranscriptomic tools to orient user choice toward the best tool for a given task. It now has a new publication and new functionality and the update is now available as its own Docker image, and on UseGalaxy.eu too.
immuneML is an open-source collaborative ecosystem for machine learning-based (ML) analyses of adaptive immune receptors and repertoires (AIRR). It comes with extensive help, and is supported by the University of Oslo.
GalaxyWorks is a company that offers commercial-grade support for Galaxy instances, and they are looking for beta testers for a new service. Galaxy Pro Researcher will offer:
- A self sign-up option with a low subscription fee
- Access to fast and versatile Galaxy Pro without usage quotas
- No need to manage your own Galaxy server
Interested in being an early adopter? See the full announcement.
Galactic Blog Activity
GalaxyWorks has also started a blog highlighting aspects of Galaxy (and sometimes their offerings too). Two posts from the past month are:
The ELIXIR Authentication and Authorisation Infrastructure (AAI) enables researchers to use their home organisation credentials or community or commercial identities (e.g. ORCID, LinkedIn, Google) to sign in and access Galaxy.
By Wolfgang Maier, Marius Van Den Beek, Björn Grüning, Sergei Kosakovsky Pond, Anton Nekrutenko, and the Galaxy Team in US, EU, and AU
By Mali Salmon-Divon.
Mali shares the feedback of two workshops run using TIaaS: one or graduate students and another one for medical doctors.
Doc, Hub, and Training Updates
Geert Bonamie (VIB Bioinformatics Core) has produced an astonishing video introduction to the GTN features.
This new tutorial will take you from raw FASTQ files to a cell x gene data matrix in AnnData format. What’s a data matrix, and what’s AnnData format? Well you’ll find out! Importantly, this is the first step in processing single cell data in order to start analysing it.
In this tutorial, we discuss recurrent neural networks, which model sequential data, and have been successfully applied to language generation, machine translation, speech recognition, image description, and text summarization.
We updated the bottom part of the hub landing page. In addition to highlighting News, Blog posts, Events, and Twitter, we added summary sections for Recent Videos, Careers, New Platforms, and Recent Pubs. We also expanded the News and Blog sections.
This new tutorial and slide deck cover how to compare both small and large sequences using both seed-based alignment methods and alignment-free methods, and how to post-process our comparisons to refine our results. Plus the theoretical background of sequence comparison, including why some tools are suitable for some jobs and others are not.
The global Life Science Trainers Community (yes, you should join) wants to highlight the important role of trainers and understand how they can be better supported. If you are, or have been a trainer, share your thoughts in this survey by March 20.
After the success of the first ‘Galaxy-ELIXIR webinar series: FAIR data and Open Infrastructures to tackle the COVID-19 pandemic’ last spring, the Galaxy community has been running a second Galaxy-ELIXIR webinar series on ‘Open Data Infrastructures to tackle COVID-19 pandemic’.
In this second edition, and for six consecutive weeks, speakers from all around the globe have been describing the latest Galaxy developments for working with SARS-CoV-2 data. If you missed them, the recordings are now available on the ELIXIR Europe YouTube channel.
Pub curation activities are on a semi-hiatus right now but a few publications referencing, using, extending, and implementing Galaxy were added to the Galaxy Publication Library anyway. Here are the new open access Galactic and Stellar pubs:
Ostrovsky, A., Hillman‐Jackson, J., Bouvier, D., Clements, D., Afgan, E., Blankenberg, D., Schatz, M. C., Nekrutenko, A., Taylor, J., Team, the G., & Lariviere, D. (2021). Current Protocols, 1(2), e31. https://doi.org/10.1002/cpz1.31
Mehta, S., Crane, M., Leith, E., Batut, B., Hiltemann, S., Arntzen, M. Ø., Kunath, B. J., Delogu, F., Sajulga, R., Kumar, P., Johnson, J. E., Griffin, T. J., & Jagtap, P. D. (2021). F1000Research, 10, 103. https://doi.org/10.12688/f1000research.28608.1
Gangiredla, J., Rand, H., Benisatto, D., Payne, J., Strittmatter, C., Sanders, J., Wolfgang, W. J., Libuit, K., Herrick, J. B., Prarat, M., Toro, M., Farrell, T., & Strain, E. (2021). BMC Genomics, 22(1), 114. https://doi.org/10.1186/s12864-021-07405-8
Ramsey, J., Rasche, H., Maughmer, C., Criscione, A., Mijalis, E., Liu, M., Hu, J. C., Young, R., & Gill, J. J. (2020). PLOS Computational Biology, 16(11), e1008214. https://doi.org/10.1371/journal.pcbi.1008214
Pavlovic, M., Scheffer, L., Motwani, K., Kanduri, C., Kompova, R., Vazov, N., Waagan, K., Bernal, F. L. M., Costa, A. A., Corrie, B., Akbar, R., Hajj, G. S. A., Balaban, G., Brusko, T. M., Chernigovskaya, M., Christley, S., Cowell, L. G., Frank, R., Grytten, I., … Sandve, G. K. (2021). BioRxiv, 2021.03.08.433891. https://doi.org/10.1101/2021.03.08.433891
Videm, P., Kumar, A., Zharkov, O., Grüning, B. A., & Backofen, R. (2021). GigaScience, 10(giaa158). https://doi.org/10.1093/gigascience/giaa158
Pires, J. G., da Silva, G. F., Weyssow, T., Conforte, A. J., Pagnoncelli, D., da Silva, F. A. B., & Carels, N. (2021). Frontiers in Genetics, 12. https://doi.org/10.3389/fgene.2021.624259
Rajczewski, A. T., Mehta, S., Nguyen, D. D. A., Grüning, B. A., Johnson, J. E., McGowan, T., Griffin, T. J., & Jagtap, P. D. (2021). . MedRxiv, 2021.02.09.21251427. https://doi.org/10.1101/2021.02.09.21251427
We are pleased to announce the 21.01 Galaxy release. As the announcement says:
Workflows are the absolute ✨star✨ of Galaxy v21.01
This include support for a workflow best practices checker, workflow reports, and tracking your workflow invocations.
The new Remote Files interface is an absolutely fantastic new way to browse your data. Browse files on many remote file services, from your Dropbox to TCGA.
Planemo is a set of command-line utilities to assist in developing Galaxy and Common Workflow Language artifacts - including tools, workflows, and training materials. These releases included numerous fixes and enhancements. Some notable changes
- Better handling of
- Display live logs when Galaxy is run in the background.
- Container register for GitHub workflows fixes
See GitHub for details.
BioBlend is a Python library for interacting with CloudMan and Galaxy‘s API. BioBlend makes it possible to script and automate the process of cloud infrastructure provisioning and scaling via CloudMan, and running of analyses via Galaxy.
There were a lot of improvements in this release. See the release notes for details
Galaxy Language Server and Galaxy Tools VS Extension assist in the development of Galaxy tools wrappers inside modern code editors.
The 0.4.x releases includes fixes and new features. See the GitHub repository for details.
...on mobile phone, while baby is sleeping.
Yvan Le Bras reminded us of several very cool things.